Ayurveda is one of the traditional medicinal system with an established history of many centuries. The primary focus of Ayurvedic medicine is to promote good health and prevent illness, rather than fight disease. Authentication of an herbal formulation is essential in order to access the quality of drugs, based on amount of their active principles, physicochemical standards and pharmacognostic parameters. In this study preparation and physicochemical analysis of Nisha amalaki churna – an Ayurvedic formulation was carried out. Nisha amalaki churna is a mixture of Curcuma longa (Turmeric) and Embilica officinalis (Amla powder) in equal proportion. Amla is a traditional remedy that may help keep blood sugar at the steady level and prevents spikes after meals. Consuming turmeric root extract can help in reducing insulin resistance that leads to rise in blood sugar levels. It also improves the functioning of Beta cells. It has antidiabetic properties. Various quality control parameters were performed for physicochemical, phytochemical tests, TLC, HPLC, HPTLC, UV, microbiological test, Ash content, heavy metal tests, LOD of raw materials as well as for finished formulation. The parameters studied for formulation can be used as a reference in developing pharmacopeial standards.

The present study was taken-up with a view to ascertain the impact of honey-enriched mulberry diet on the sericultural productivity vis-à-vis its energetics in Bombyx mori. The sericultural productivity has been assessed with reference to the larval body growth, silk gland growth, gland-body ratio, silk protein synthesis, cocoon traits, silk traits and female reproductive traits. The honey-enriched mulberry diet positively reinforced the economic parameters of sericulture and additionally reduced the production of floss which is considered the sericultural wastage. In order to trace the relation between sericultural productivity and energy metabolism, the energetics of silk production and egg production has been examined by assaying the energy parameters of glycolytic oxidative phosphorylation and transdeamination in the larval silk gland and the pupal-adult fat body.  The utilization patterns of glucose through succinate dehydrogenase (SDH) activity and free amino acids through aspartate aminotransferase (AAT), alanine aminotransferase (ALAT) and glutamate dehydrogenase (GDH) were interpreted in terms of glycolytic oxidative phosphorylation and non-glycolytic transdeamination respectively.  The trends in enzyme activities vis-à-vis the utilization of glucose and free amino acids indicated that the energy needs of both silk production and egg production are majorly met through a transdeamination and it is supplemented by glycolytic oxidative phosphorylation. The honey-enriched mulberry diet positively reinforced the silk production in the larval silk gland through its stimulatory effect on both glycolytic oxidative phosphorylation and transdeamination. However, it selectively boosted egg production in female adult moth by stimulating oxidative phosphorylation, but showed no significant effect on transdeamination in pupal and adult stages.

The essential oil of Aechmenthara gossypina (Wall.) Nees. was examined by GC and GC-MS analyses. Total of forty five components were identified which represented 89.7%% of the total oil. The oil was found to be rich in oxygenated sesquiterpenes contributing up to 43.6% of the oil. The sesquiterpene hydrocarbon constituted 42.9% while oxygenated monoterpenes 1.1%, monoterpene hydrocarbons 0.7% and others constituted 1.4% of the oil. The major constituents of the oil were identified to be guaiol (30.0%), Germacrene D (14.6%), α-muurolol (8.3%), β-caryophyllene (9.5%) and kessane (5.3%). The essential oil of A. gossypina showed maximum inhibitory effect (21 mm) against Enterococcus faecalis followed by Staphylococcus aureus (20 mm), Bacillus subtilis (18 mm) and Escherichia coli (17 mm). The lower zone of inhibition was observed against Xanthomonas phaseoli (10 mm). It is evident from the recorded data that the oil sample demonstrated a higher level and broader spectrum of activity against all ten pathogens, which is comparable to or some time higher than those of standard antibiotics used as positive control.

The purposeful necessities of skincare textiles have led to the pioneering use of diversity of natural plants with therapeutic properties for medical applications. Cassia auriculata is commonly called as avaram belongs to Fabaceae family.   The Cassia auriculata leaves are one of the exceptionally important natural plants available in the all areas with abundant germ-free properties. In this present investigate work the Cassia auriculata leaves were collected and extracted it was coated on banana fabric. The extract was tested under qualitative antimicrobial phyto-chemical screening and the test results revealed the presence of antimicrobial constituents. The anti-bacterial and anti-fungal activity of Cassia auriculata leaf  of 6% and 12% concentrated ethanolic extracts were analyzed using standard AATCC 147and AATCC 100 tests against both gram positive bacterial pathogens namely  staphylococcus aureus, klebsiella pneumoniae and gram negative bacterial pathogens pseudomonas auruginosa, escherichia coli  and aspergillus nigar fungi. The extract was tested under qualitative phytochemical screening, the results expressed that the occurrence of various phytochemicals. The activity test results also shows that theCassia auriculata treated samples have superior antibacterial and antifungal activity by zone of inhibition.

Ceratotheca triloba (Bernh.) E. Mey. ex Hook.f is native to tropical and subtropical  African countries and is used in traditional medicine to treat painful menstruation, stomach cramps, nausea, fever and diarrhoea. Anecdotal reports of its effects in cancer treatment and prevention, with many successful cases, have warranted that these pharmacological properties be scientifically validated. A bibliographic search was conducted using the key words "Ceratotheca", "anticancer", and "antitumor" along with cross-referencing. No clinical or animal cancer studies were identified and only two in vitro cell-culture-based studies were reported; these indicate that extracts of C. triloba may alter the growth of several types of cancer cell lines. This review summarizes the results of anthraquinones and emphasizes the aspects that warrant future research to explore the anthraquinones in C. triloba for their anticancer activities.

Substance use disorder (SUD) is a condition in which the use of one or more substances leads to a clinically significant impairment or distress. Common Abused Substances worldwide are Opiates, Stimulants, Sedatives-Hypnotics, Anabolic- steroids, Marijuana, Phencyclidine, Hallucinogens, Alcohol, Nicotine, Inhalants and Tobacco. These substances all directly activate the brain's reward system and produce feelings of pleasure. The activation may be so strong that people intensely crave the substance. They may neglect normal activities to obtain and use the drug. Substance use disorders can develop whether or not a drug is legal, is socially acceptable, or has an accepted medical use (with or without a prescription). The terms "addiction," "abuse," and "dependence" have traditionally been used in regard to people with substance use disorders. Ayurveda has documented the ‘body-mind’ relationship years ago. Mental health is the foundation for effective communication, learning, emotions, thinking and self-esteem in an individual. Unmada is one of the major mental disorders described in Ayurveda, which is referred to as insanity, mental disorder and madness. Unmada covers many of the mental disorders and a person suffering from it may or may not be aware of the external environment.

Coronavirus disease (COVID 2019) is an infectious disease caused by a new virus. The disease causes respiratory illness (like the flu) the symptoms such as cough, fever and in more severe cases, difficulty breathing and death. ^[28] It is caused by a member of the coronavirus family that has never been encountered before. Like other coronaviruses, it has come from animals. It first emerged in the Chinese city of Wuhan in November 2019. The World Health Organisation has declared it a Pandemic. There is a high global risk according to the WHO reports. This paper discusses the Antiviral activities and immune-boosting properties of selected medicinal plants which have been studied on other viruses which could be a solution for Coronavirus infection">

Roots of Prismatomeris glabra (PG), from the Rubiaceae family, have long been traditionally used by indigenous people to maintain their wellness. The root is also believed to have an aphrodisiac effect. To prove whether this claim was true, a study was conducted to determine the effects of aqueous extract of PG root on sexual function of male mice. Sexual behaviour of mice that received a daily dosage of 500 mg/kg/d p.o. was determined when males were introduced to hormonal-induced sexually receptive females. Copulating was observed at four sessions: one before any administration was given, and the second, third and fourth sessions took place following 7, 14 and 21 days of daily dosage, respectively. The number of mounts and intromissions, latency to the first mount, latency to first intromission and hormonal levels were determined. Effects of PG (500 mg/kg/d p.o. for 2 weeks) on testosterone, luteinizing hormone (LH) and corticosterone levels in castrated and intact male mice were also determined using EIA method. The control group (which received similar treatment to the PG-treated group) and normal group (which did not receive any treatment except for oral gavages) were given 0.9% normal saline.  PG-treated mice had a greater frequency of mounting than the control group in the first (p=0.021) and second (p=0.032) copulation sessions. PG-treated mice also showed greater intromission duration (p=0.01) and frequency (p=0.02) than the control group in the third session. Serum testosterone and luteinizing hormone of PG-treated mice were not different from control and normal groups. Administration of PG for 2 weeks to castrated mice also did not show any testosterone level in the blood. The same dose of PG did not influence testosterone and corticosterone levels in intact mice either.  The aqueous extract of PG root is indeed found to have a potential for aphrodisiac use. A further study of its specific mechanism of action is recommended.

Women are worshipped as God due to her ability of bringing new life on earth. During reproductive period of women’s life there are varieties of ovarian cysts formation which leads to menstrual disturbance which might further lead to infertility. In recent years there is gradual rise in detection of ovarian cysts due to advance diagnostics. There is prevalence of 17 to 44% of ovarian cysts formation during reproductive phase. In this article, a case report regarding a patient of age 30 years having previous H/O Bilateral chocolate cyst with both tubes thick with endometriosis and laparoscopic findings s/o impatent tubes. For which patient had undergone laparoscopic aspiration. She was again diagnosed with recurrence of chocolate cyst by ultrasonography for that she came in our OPD for treatment.  In Ayurveda it is stated that shuddha yoni, ambu, beej and kshetra are needed for Garbhadharan. Treatment plan was Shodhana, Uttar basti with lekhan dravyas, and Shamana chikitsa. After 3 months of treatment regimen ultrasonography and hysterosalpingography were repeated and reports revealed that previous mentioned Left ovarian complex/haemorrhagic cyst is not seen and tubes are patent. Hence, case study confirms that we can treat chocolate cyst with the help of Uttar basti and shamana chikitsa which acts as lekhan and normalizes vata dosha and rakta dosha.

The increasing demand to produce secure and cost-effective healthcare nanodevices is at the forefront of research in nanotechnology. The present work reports a simple and eco-friendly synthetic method for silver nanoparticles using the bark aqueous extract of Mangifera indica (MI-AgNPs) for the management of inflammation. MI-AgNPs were obtained following incubation of the mixture of the plant extract with silver nitrate solution (10:50 v/v).  The sample was biophysically characterized using Ultraviolet Visible spectroscopy (UV-Vis), Fourier Transform Infrared spectroscopy (FTIR), Powder X-Ray Diffraction (PXRD) and Dynamic Light Scattering (DLS) technics while egg albumin denaturation and carrageenan-induced rat paw edema model were used to evaluate its anti-in?ammatory activity. The changing colour of the reaction mixture and UV-Vis absorbance spectrum validated the formation of MI-AgNPs, showing a characteristic peak at 410 nm. FTIR spectra showed the main reducing groups from the bark extract and PXRD highlighted the crystalline nature of the MI-AgNPs. The hydrodynamic diameter was found to be 104 nm with a polydispersity index of 0.27. Anti-inflammatory activity of MI-AgNPs was observed in a dose-dependent manner. In heat-induced egg albumin denaturation method, MI-AgNPs exerted maximum protection of 80 % at 200 µg/mL (highest tested concentration) while aspirin used as reference drug exhibited 67 % protection. Similarly, the oral pre-treatment of rats with MI-AgNPs caused significant (P<0.001) inhibition of carrageenan-induced rat paw edema with a maximum inhibition of 89 % at the dose of 200 µg/kg. These findings infer that Mangifera indica bark aqueous extract-mediated silver nanoparticles could be considered as an interesting solution for the development of therapeutic strategies against inflammation related diseases

Endometrial hyperplasia with PCOD is one problem in female infertility .Its prevalence is 12.8% in society¹. It is very difficult to treat when the patient comes after receiving all hormonal and modern treatment. It is the need of time to establish an affective Ayurvedic treatment in such cases. Here is a case discussed of 24 years female having secondary infertility due to endometrial hyperplasia with PCOD Who has already received modern treatment that is Dilatation and curettage and then Hormonal therapy Then Ayurvedic therapy given here was Yoga basti and Uttarbasti  for 3 cycles after treatement she menstruate normally without hormones and get conceived in next preceding month.  

The main objective of Ayurveda is to protect health of the healthy and to alleviate the disorders of the diseased. Ayurveda deals with good, bad, happy and unhappy life and it’s all other aspects. Entire misery related to both mind and body depends on ignorance and the entire happiness resides in pure knowledge.COVID-19, caused by the virusSARS-CoV-2, is the pandemic which the entire world is currently facing. To find out an effective treatment against it and save the humanity from the havoc it created is the greatest challenge before mankind at present. Ayurveda considers that deranged air, water, place and time are the cause of epidemics. Even when these 4 epidemic-producing factors are present, a person who has been properly treated with preventative care will be immune against the diseases. Truthfulness, benevolence, charity, offerings, worship of gods,  calmness, self-protection, residence in healthy places, observance of celibacy and company of those who are observing celibacy, reading religious scriptures, narratives of  great sages, following  teachings of religious, pure and those regarded by the elders-this is the management for the protection of life. These measures should be adopted by the healthy people at personal level for the prevention of infection. For the diseased, use of jeevaneeya(promoting long life), rasayana (anti-aging, rejuvenating) balya (strengthening ) and medhya (enhancing intelligence) drugs may prove to be useful.Ashwagandha, Guduchi, Shunthi, Tulsi, Vasa, Kantakari,Bhaarangi,Marich,Daalcheeni,Haridra are the herbs very effective in strengthening immunity and protecting the respiratory system. Along with this, Yoga, meditation and enchanting of Vedicmantras should be regularly practiced for maintaining a healthy lifestyle during and post CoV outbreak.Persons who are desirous of a life which is the means to obtain dharma (religious merit, righteousness), artha (wealth) and sukha (happiness), should bestow utmost faith in the teachings of Ayurveda.One should maintain a balanced mind both during calamity and prosperity.

Diabetes mellitus (DM) is a chronic disease caused by the inability of the pancreas to produce insulin or the body cannot use it effectively. Treatment of DM has been using antihyperglycemic drugs, in the form of oral antidiabetic and insulin injections. The administration of these chemical drugs can only reduce microvascular complications, while macrovascular complications cannot be reduced. DM treatment needs additional natural antioxidants, one of which is rosella flower. This research will analyze the effect of rosella flower herbal drink on blood glucose levels at a time. A total of 20 respondents were recruited by purposive sampling, divided into 10 respondents in the intervention group and 10 respondents in the control group. The intervention group consumed a 500 mg rosella flower herbal drink every day for three weeks. In the group control consuming tea one bag of Java bag every day for three weeks. ANOVA test was used to analyze blood glucose levels at a time. The research proves that the rosella flower herbal drink can significantly reduce blood glucose levels. There were significant differences in blood glucose levels between the intervention and control groups.

Triphala is the most ancient mystical herbal drugs which are used in Indian traditional medicine system Ayurveda. It is the combination of three fruits in the ration of 1:1:1 and having great pharmacological actions. It is helpful in ailments of dosha vata, pitta and kapha; increases digestive power, remove toxins from the body having good anti-oxidant properties. In recent years there are many studies and experiments done on triphala that suggests its action as immunomodualtory, anti-ageing and anti-diabetic.

: Maranthes polyandra is a plant used in Michika Adamawa state, the Northeastern part of Nigeria as fruits and the vegetable to manage the condition that causes a tissue or organ to deteriorate over time, such as hemorrhage and anemia.  The aim of this study was to isolate, characterize, and evaluate the antibacterial, especially the facultative foodborne pathogen (E. Cole), as well as the isolated compounds from the leaf extract. Methods: Extraction of the crude extract was assessed through methanol soaking, extract obtained from Retro-vap, Isolation using, TLC, CC, and IR. Characterization was obtained and done using GC-MS, NMR, and FTIR. Biological activity was evaluated using the desk diffusion method. The results: The result shows three pure compounds isolated which are xanthoxylin, beta-eudesmol, and Luteolin. Conclusion: The presence of phytochemical compounds such as Beta-eudesmol, Luteolin, and Xanthoxylin could be responsible for the antibacterial activity of Maranthes polyandra. This is the first time chemical constituent was isolated from this plant. Thus, considered a novel study. ">